Publication: JAMADesign: Multicenter, randomized, double-blind, placebo-controlled trial performed in six hospices in the Netherlands of 162 patients with a life expectancy of three or more days. Administration of subcutaneous scopolamine butylbromide, 20 mg four times a day (n = 79) or placebo (n=78) in the 157 patients included in the primary analysis.Results: A death rattle occurred in […]
The exact ways in which COVID-19 is impacting children, particularly those under age 12, is still being examined. Reported at the IDWeek conference, Arkansas health officials presented data demonstrating the severe impact that the fast-moving Delta variant of COVID-19 can have on children. Key findings: From January 2021, the Delta variant led to 42% more […]
In practice, “standard” duration of antibiotic therapy is often based on archaic studies. Newer evidence shows that shorter durations are often a better choice and that antibiotic resistance is more likely to develop with longer durations of therapy. Here are the recommendations applied to four commonly treated infections.
Curious about the long-term impacts of COVID-19? A new study that involved 2,433 hospitalized patients found that the most common symptoms after one year were fatigue, sweating, chest tightness, anxiety, and myalgia. The study, conducted in Wuhan, China, one of the global epicenters of the pandemic, also found that patients with severe disease had more […]
Evidence is mounting that much of the concern about waning immunity to COVID-19 is overstated and that vaccines provide high levels of protection against the respiratory disease and its variants over the long-term. Immunologically, plasmablast and B-cell response after mRNA vaccination is long-lived and memory B cells increase over at least six months. And in […]
This BMJ editorial examines whether approaches better equipped to compare rates of menstrual variation in vaccinated versus unvaccinated populations are needed, based on the reports of changes to periods and unexpected vaginal bleeding after vaccination. The US has taken the first step, earmarking $1.67M from the National Institutes of Health to encourage research.
Vaccinations are up and COVID-19 cases continue to decline, but healthcare will forever be changed by the pandemic. The telehealth revolution is upon us, and health disparities are finally being addressed. Doctors and patients are working together to define what constitutes “necessary” healthcare. Discover what else the future holds for healthcare in a post-pandemic world.
Source: MedPage Today (from JAMA Oncology)Design: Analysis was from a previously published prospective cohort study that evaluated the rates of antibody response to Pfizer’s vaccine in 102 cancer patients who were on active treatment compared with 78 healthy controls. A fourth of the patients were undergoing treatment for lung cancer, 26% for gastrointestinal cancers, and […]
Antibodies against COVID-19 continue to perplex and confound physicians and research scientists. Although people who have gotten COVID-19 or been vaccinated against the respiratory disease develop a humoral immune response that protects them from reinfection, those antibodies decline over time, leaving people vulnerable to reinfection. Understanding why this happens is critically important to modeling how […]
Nearly a third of all Americans (100 million people) have now been infected with COVID-19. And scientific evidence shows that natural immunity from infection is durable and long-lasting. So why is it then that inoculations continue to be pushed for all people regardless of whether they have contracted COVID-19 or not? And why isn’t natural […]