Haymarket MediaHypertension Journal Study: Evaluating ARBs vs. ACE Inhibitors Safety Outcomes

Findings: Primary outcomes included AMI, HF, stroke, and CVEs; 51 secondary and safety outcomes included angioedema, cough, syncope, and electrolyte abnormalities. ACE inhibitors were associated with a significantly increased risk of four secondary and safety outcomes compared with ARBs.Design: Multinational cohort study; Patients: ~2.3M ACE, ~674K ARB 

Wyanoke GroupCertain Antihypertensive Drugs Yield Less Memory Decline in Older Adults

According to Daniel A. Nation, PhD, associate professor of psychological science at University of California, Irvine: “Studies of angiotensin II receptor blockers and ACE inhibitors have suggested these medicines may confer the greatest benefit to long-term cognition, while other studies have shown the benefits of calcium channel blockers and diuretics on reducing dementia risk.”

The Cleveland Clinic FoundationACE Inhibitor and ARB Therapy: Practical Recommendations

Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) are cornerstones of cardiovascular disease therapy. In this article (registration required) from the Cleveland Clinic Journal of Medicine, the author provides insight and commentary on whether ACE inhibitors are better than ARBs. The conclusion is there is more to the story and the evidence than […]