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Practical Neurology
Muscle cramps are common in the general population, with reported prevalences ranging from 37% to 95%. When frequent or severe, muscle cramps can cause prolonged postcramp soreness and can diminish quality of life by disrupting sleep, limiting physical activity, and provoking anxiety about symptom recurrence.
Emergency Medicine August 20th 2025
GoodRx for Healthcare Professionals
“Based on research, magnesium is unlikely to help with leg cramps. But vitamin K supplements may reduce the intensity, frequency, and duration of leg cramps.”
Clinical Pharmacology July 24th 2025
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