Pediatric B-cell acute lymphoblastic leukemia (B-ALL) is the most common malignancy seen in children and adolescents and young adults (AYAs). This article highlights two recent studies that provide novel evidence of the association between obesity and increased risk of high-risk B-ALL and the effectiveness of a non-pharmacologic intervention for reducing minimal residual disease (MRD) risk.
According to the American Academy of Pediatrics (AAP) recommendations in “COVID-19 Interim Guidance: Return to Sports”, a positive cardiac screen or other concerning findings from a recovered COVID-19 youth patient should prompt an electrocardiogram (EKG) and potential referral to a pediatric cardiologist. The updated guidance has a focus on cardiac evaluation.
The NCI sponsors and funds the consortium, a multidisciplinary cooperative research organization devoted to the study of correlative tumor biology and new therapies for children with primary central nervous system tumors. New members are chosen through a competitive process based on several characteristics, including clinical trial infrastructure and expertise in basic and translational science.
In this article from Pediatrics, the authors explore severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and its impact on the COVID-19 transmission. The argument concludes that children, particularly school-aged children, are far less important drivers of SARS-CoV-2 transmission than adults.