In what is believed to be the most comprehensive molecular characterization to date of HPV-negative head and neck squamous cell carcinomas (HNSCCs), researchers have clarified the contribution of key cancer-associated genes, proteins and signaling pathways in these cancers, while proposing possible new treatment avenues.
According to new research from investigators with the Johns Hopkins Kimmel Cancer Center and its Bloomberg-Kimmel Institute for Cancer Immunotherapy, a microbe found in the colon and commonly associated with the development of colitis and colon cancer also may play a role in the development of some breast cancers.
These evidence-based guidelines from the American Society of Hematology (ASH), the International Society on Thrombosis and Haemostasis (ISTH), the National Hemophilia Foundation (NHF), and the World Federation of Hemophilia (WFH) are intended to support patients, clinicians, and health care professionals in their decisions about management of VWD, a common inherited bleeding disorder.
In the two-and-a-half-hours of suggested physical activity every week, we should be getting 10 minutes of heart-pumping exercise into every session. But what about those who like to jog in the morning and those who love pumping the iron after work? Who is better off? If you believe a 2019 study, it really doesn’t matter […]
The term abscopal effect (from Latin, ab, meaning “away from,” and scopus, meaning “target”) was coined in 1953, specifically referring to effects of ionizing radiation outside the radiated tumor volume. Does the evidence show that, contrary to widely held perception in the field, the abscopal effect is exceedingly rare and is not clinically relevant when […]
Now that 2021 is here, you’re not alone in trying to possibly lose weight. In fact, an estimated 45 million Americans go on some sort of diet each year. But are you sabotaging yourself even before you get started? As you think about your health goals in this new year, be sure you’re not falling […]
The British Medical Journal’s executive editor, Kamran Abbasi, pens a commentary about DANMASK-19, the first trial of mask use during COVID-19 and its controversial “negative” results. Abbasi claims that disagreement among experts, especially about interpretation of a study, is a common occurrence and “the usual business of science,” but the influence of social media has […]
In the new study, published December 1, 2020 in the open-access journal eLife, researchers from UC San Francisco showed the drug, ISRIB, produced rapid restoration of youthful cognitive abilities in aged mice, accompanied by a rejuvenation of brain and immune cells that could help explain improvements in brain function.
Getting out and enjoying the sunshine seems to be more important than ever right now, and some studies indicated that not getting enough of vitamin D may be a risk factor for all-cause mortality, and numerous researchers have concluded that we should all probably be getting a little more of it. According to the available […]
Published in Clinical Advances in Hematology & Oncology, this article presents an overview of the currently available monoclonal antibody treatments in MM, discussing the clinical value, significant potential, and possible limitations of these immunotherapeutic approaches to driving deeper responses and achieving longer overall survival among patients with a challenging disease.