A new study published in Pediatrics concludes that there is a quick clinical recovery and excellent short-term outcomes for adolescents who develop COVID-19-related vaccination-associated myocarditis (C-VAM). The average age in the study was 15, and close follow-up and further studies are needed to understand the long-term implications and mechanism of these myocardial tissue changes.
BMJ’s investigation findings raise questions about data integrity and regulatory oversight concerning Pfizer’s vaccine trial. A regional director told the BMJ that Pfizer falsified data, unblinded patients, employed inadequately trained vaccinators, and was slow to follow up on adverse events reported in the pivotal phase III trial.
Evidence is mounting that much of the concern about waning immunity to COVID-19 is overstated and that vaccines provide high levels of protection against the respiratory disease and its variants over the long-term. Immunologically, plasmablast and B-cell response after mRNA vaccination is long-lived and memory B cells increase over at least six months. And in […]
This BMJ editorial examines whether approaches better equipped to compare rates of menstrual variation in vaccinated versus unvaccinated populations are needed, based on the reports of changes to periods and unexpected vaginal bleeding after vaccination. The US has taken the first step, earmarking $1.67M from the National Institutes of Health to encourage research.
Source: MedPage Today (from JAMA Oncology)Design: Analysis was from a previously published prospective cohort study that evaluated the rates of antibody response to Pfizer’s vaccine in 102 cancer patients who were on active treatment compared with 78 healthy controls. A fourth of the patients were undergoing treatment for lung cancer, 26% for gastrointestinal cancers, and […]
Nearly a third of all Americans (100 million people) have now been infected with COVID-19. And scientific evidence shows that natural immunity from infection is durable and long-lasting. So why is it then that inoculations continue to be pushed for all people regardless of whether they have contracted COVID-19 or not? And why isn’t natural […]
The two new studies in the Morbidity and Mortality Report compared data from July and August 2021 – when delta was dominant to the earlier period in the pandemic – and found that about 1.4 of every 100,000 children/adolescents were hospitalized for COVID-19, nearly 5x the weekly rate in late June and close to the […]
Publication: JAMAMethod: Electronic health record (EHR) data from 8 health systems over seven 4-week surveillance periods to identify and assign gestational ages for spontaneous abortions and ongoing pregnancies; analyzed and compared odds of receiving a COVID-19 vaccine in the 28 days prior to spontaneous abortion and ongoing pregnancies.Results: Of 105,446 unique pregnancies, 13,160 spontaneous abortions […]
As the influenza season will coincide with the ongoing COVID-19 pandemic, it’s perfect timing for the release of the CDC Advisory Committee on Immunization Practices (ACIP) influenza vaccination updated guidance. The comprehensive report indicates that COVID-19 vaccines can be co-administered with other vaccines, including influenza vaccines like egg-based flu vaccines and cell culture-based inactivated and […]
Publication: Blood AdvancesStudy Design: Prospective study with unmatched health care workforce control group, receiving either Moderna or Pfizer COVID vaccination.Study Population: 23 patients with CLL (61%), lymphoma (39%) (including DLBCL), MCL (13%) and 4% with less common lymphomas.Outcome: Lymphoma patients had significantly lower anti-S IgG titers 28 days post-vaccination compared with controls. Related Article: Efficacy […]