Trigonelline, a natural compound in coffee, has been linked to improved muscle strength and longevity by promoting mitochondrial function and NAD+ synthesis, key in combating age-related muscle loss.

Recent systematic reviews suggest a subtle increase in NMOSD and MS risks post-COVID-19 vaccination, primarily affecting genetically susceptible individuals.

Among the approved SGAs for MDD, no single medication stands out as the first choice; decision-making is guided by individual patient profiles and side effect considerations.

Lithium continues to be recognized as the most reliable mood stabilizer for bipolar disorder patients with a history of mania, necessitating precise management of dosages to prevent significant side effects.

Rejoyn represents a significant advancement in the treatment of major depressive disorder, requiring prescription use and integrating brain-training exercises developed by leading mental health experts.

Rapunzel syndrome, though rare, presents significant challenges in diagnosis and treatment, involving both psychiatric and gastrointestinal expertise. Understanding its clinical and psychological aspects is vital for effective management.