5 Diabolically Difficult Diseases to Diagnose

A diagnosis that is made after all differential diagnoses have been ruled out – a diagnosis of exclusion (DOE) – is a challenge for the physician. Despite the DOE being verifiable, the diagnostic tests needed simply cannot be performed – think brain biopsy – or are too difficult to perform. These five diseases are notoriously tricky to diagnose and will test your documentation skills, as well as your attention to detail.