Articles related to Oncology

A growing body of observational evidence links coffee consumption with lower risks of several cancers, particularly hepatocellular and endometrial cancer, but experts caution that current data do not justify prescribing coffee as a cancer-prevention strategy.

A long-term analysis of nearly 160,000 US postmenopausal women found that brain and central nervous system cancer risk increased with higher residential radon concentrations, adding to limited evidence that radon may affect organs beyond the lung.

Older adults with advanced or metastatic urothelial carcinoma treated with enfortumab vedotin experienced substantially higher rates of severe toxicity and treatment discontinuation than younger patients, while survival outcomes appeared similar across age groups.

Analysis of postmenopausal ovarian tissue from 28 women found that ovaries continue to undergo molecular remodeling decades after menopause, with age-related increases in inflammatory and tissue-remodeling pathways that overlap with biologic processes observed in ovarian cancer.

A young child with an inherited tumor-predisposition syndrome develops recurrent bilateral visual decline after completing first-line chemotherapy for a radiographically diagnosed optic pathway tumor, requiring reassessment of treatment urgency, systemic options, and surveillance.

Gliomas and ependymomas appear to reuse developmental hierarchies, progenitor states, and neural-circuit signals that shape tumor heterogeneity and treatment response, although many proposed therapeutic vulnerabilities remain supported primarily by preclinical evidence.