Articles related to Gastroenterology
Gallstone Disease May Be Predictor of Pancreatic Cancer
A new study has found that patients with pancreatic ductal adenocarcinoma were six times more likely to have had cholelithiasis or cholecystitis in the year before diagnosis compared with the general population.
Gastroenterology May 24th 2022
Capsule Endoscopy in Gastrointestinal Disease: Evaluation, Diagnosis, and Treatment
Capsule endoscopy, also known as wireless capsule endoscopy or video capsule endoscopy, is a noninvasive procedure that uses a swallowed capsule-shaped miniature camera for direct visual and diagnostic evaluation of various gastrointestinal (GI) diseases. Although originally intended as a tool to examine the small intestine, which is mostly beyond the reach of conventional endoscopy, capsule endoscopy is now being used to examine the entire length of the GI tract.
Gastroenterology May 3rd 2022
Study Dispels Myths on Intermittent Fasting for Weight Loss
New research into intermittent fasting has found that the practice is generally safe, producing few gastrointestinal, neurologic, hormonal, or metabolic effects. Additionally, the research found that intermittent fasting is on par with traditional calorie-restricted diets for weight loss.
Cardiology April 19th 2022
FDA Says No to Vadadustat Approval Due to Safety Concerns
The US Food and Drug Administration (FDA) has said “no” to Akebia Therapeutics’ drug application for vadadustat, a therapy to treat anemia due to chronic kidney disease. Vadadustat is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor designed to mimic the physiologic effect of altitude on oxygen availability. The FDA cited safety concerns as the main reason for it rejecting the application.
Family Medicine/General Practice April 12th 2022
Dramatic Changes in the Recommended Approach to Diverticulitis
New guidelines recommend that internists treat uncomplicated diverticulitis in an outpatient setting without the use of antibiotics. The new guidelines on diagnosis and management of patients with diverticulitis have been published by the Annals of Internal Medicine. And they are stirring up debate among physicians.
Emergency Medicine April 12th 2022
Epidermal Growth Factor Receptor Inhibition (EGFRi) in EGFR–Amplified Gastroesophageal Cancer: Retrospective Global Experience
Sixty patients with EGFR-amplified gastroesophageal adenocarcinoma(GEA) received EGFRi, including 31 of 60 patients (52%) with concurrent chemotherapy. Across treatment lines, patients achieved a 43% objective response rate with a median PFS of 4.6 months. Typical OS with first-line initiation of non-EGFRi therapy in patients with EGFR-amplified GEA is 11.2 months, as determined by analysis of a deidentified clinicogenomic database. Despite this benefit, analysis of that database for January 2011 through December 2020 suggests that only 5% of patients with EGFR-amplified GEA received EGFRi.
Gastroenterology April 5th 2022