Articles related to Gastroenterology

Among nearly 1 million UK adults, preference for very hot beverages and consumption of at least six hot drinks daily were associated with higher esophageal squamous cell carcinoma risk, but not materially with adenocarcinoma.

Updated joint ESPGHAN/NASPGHAN guidelines for pediatric Helicobacter pylori infection emphasize antimicrobial stewardship, susceptibility-guided therapy, and more selective testing strategies. The recommendations also introduce several changes regarding screening, incidental findings, and management of associated conditions.

New consensus guidance favors once-daily oral iron and simplified IV administration, including fewer test doses, premedications, and infusion visits. Several recommendations depart from established protocols and require formulation-specific clinical judgment.

Daily consumption of sugar-sweetened beverages was associated with more than double the risk of gastric cancer in two large U.S. prospective cohorts, although the findings did not establish causality and require confirmation in additional studies.

A multiplexed cytokine and tumor-antigen mRNA immunotherapy produced durable tumor responses in mouse models of pancreatic ductal adenocarcinoma, with approximately half of treated animals remaining disease-free for up to one year, although clinical relevance remains unproven.

The American Gastroenterological Association issued nine best practice statements on colorectal and esophageal surveillance in older adults. Recommendations emphasize individualized decisions, life expectancy, treatment candidacy, procedural risks, and patient preferences.