Research shows that the “old” 2015 recommendation would only identify about half of Americans with prediabetes and undiagnosed type 2 diabetes. Based on this data, the US Preventive Services Task Force has lowered the recommended screening age from 40 to 35 years in asymptomatic, nonpregnant adults who are overweight or obese.
Can you differentiate between bradykinin-mediated angioedema and the more common histamine-mediated angioedema? How significant is a delayed diagnosis? Do you favor on-demand or preventative therapy? What is the recommended therapy? Access to specialist care and effective treatment in the past 10 years has improved the quality of life and reduced the mortality rate in patients […]
MDCalc.com offers this helpful tool, which calculates creatinine clearance (CrCl) according to the Cockcroft-Gault equation. The tool also allows height input, which analyzes BMI and provides a modified estimate and range.
Often undiagnosed due to its unspecific symptoms, hereditary angioedema (HAE) is a tricky condition that causes many patients unnecessary suffering with unnecessary surgeries and invasive diagnostic/therapeutic interventions. Read on to educate yourself on some of the alarming numbers on the orphan disease.
Which specialties will be most affected by changing age demographics among doctors? That’s the question the Association of American Medical Colleges (AAMC) asks in their latest survey of “Active Physicians by Age and Specialty”, which tallied up the results of 935,000 practicing physicians in the US. Where does your specialty fall on the list?
After diagnosis during a partial mastectomy, this patient’s estimated blood loss was 58 mL, causing anemia and requiring a red blood cell transfusion along with ventriculoperitoneal drain placement. With a substantive bleeding history before the diagnosis, what would you do next with this patient? Work her up for von Willebrand disease? Do a complete blood […]
Publication: JAMA Oncology Objective: With NSCLC having relatively poor outcomes and the significant data supporting the use of metformin as an antineoplastic agent, the researchers wanted to compare overall or progression-free survival in chemoradiation alone vs. chemoradiation + metformin stage III NSCLC patients. Design: Randomized clinical trial, open-label, phase 2 study; 167 eligible patients
Findings: Primary outcomes included AMI, HF, stroke, and CVEs; 51 secondary and safety outcomes included angioedema, cough, syncope, and electrolyte abnormalities. ACE inhibitors were associated with a significantly increased risk of four secondary and safety outcomes compared with ARBs.Design: Multinational cohort study; Patients: ~2.3M ACE, ~674K ARB
According to the SUSTAIN FORTE study presented online in The Lancet Diabetes & Endocrinology, doubling the dose of semaglutide (Ozempic) might be a helpful option for people not achieving glycemic goals. Still, some researchers aren’t convinced this is a sound strategy – “statistically significant but barely clinically relevant” — suggesting opting for another agent when […]
According to the interim guidance, “remote-learning highlighted inequities in education, was detrimental to the educational attainment of students of all ages, and exacerbated the mental health crisis among children and adolescents.” The AAP continues to recommend that all staff and students who are 2 years or older wear face masks unless medical or developmental conditions […]