Articles related to Endocrinology, Diabetes, Metabolism

Reports of relationship changes after GLP-1–associated weight loss have prompted the label “Ozempic divorces.” The article draws on anecdotes and bariatric-surgery research, neither of which establishes that these medications increase divorce risk.

Growing interest in testosterone for menopause extends beyond its best-supported use for distressing low sexual desire in postmenopausal women. An expert explainer reviews that evidence while highlighting uncertain broader benefits, dosing challenges, and limited long-term safety data.

Among middle-aged women taking semaglutide, menopause hormone therapy use was associated with greater weight loss in an observational conference study. Tirzepatide findings were less consistent, and the results have not undergone journal peer review.

Among 293,872 UK Biobank participants without baseline cardiovascular disease or lipid-lowering therapy, HDL-C retained an inverse association with incident ASCVD after accounting for apoB and triglycerides. The observational findings do not establish a protective biological effect.

Among 49,440 adults identified as Arab American in a Texas health system, 15.2% had documented ASCVD and 3.4% met the study’s premature-disease definition. Identification methods and encounter-based age classification limit interpretation.

A secondary analysis of CARBFUNC found divergent lipid responses to a very-low-carbohydrate, high-saturated-fat diet in adults with obesity. ApoB remained largely unchanged despite higher LDL-C, while long-term cardiovascular outcomes remain unresolved.