Articles related to Endocrinology, Diabetes, Metabolism

A BMJ systematic review of 69 trials found calcium and vitamin D supplementation provided little to no reduction in fracture or fall risk among nearly 154,000 older adults studied.

PCOS was associated with significantly elevated risk for breast, uterine, ovarian/fallopian tube, and cervical cancers in a matched cohort of more than 2.5 million women.

Premature menopause was linked to a 40% higher long-term risk of coronary heart disease in a pooled analysis of more than 10,000 women followed across six cohort studies.

Menopausal hormone therapy users showed significantly higher bone mineral density at the spine and hip than non-users in a retrospective cohort of 387 postmenopausal women.

Hormone therapy status was associated with differences in diet, physical activity, and sleep guideline adherence in a cross-sectional analysis of more than 10,000 women.

The FDA approved olezarsen (Tryngolza), an apoC-III antisense inhibitor, as an adjunct to diet for reducing triglycerides and acute pancreatitis risk in adults with severe hypertriglyceridemia, based on phase 3 data showing an 85% reduction in pancreatitis events compared with placebo.