Registry-recorded antibiotic prescriptions beginning in later childhood were associated with IBS at age 24 in a Swedish cohort. Higher prescription counts accompanied higher odds, but the findings do not establish causality or when symptoms began.

A review of pediatric inflammatory bowel disease describes how growth and inflammation alter biologic drug exposure. Evidence supporting proactive monitoring is strongest for anti-TNF therapies, while pediatric targets for newer agents remain less certain.

A seven-year-old initially presenting with isolated palpable purpura developed joint and abdominal symptoms consistent with IgA vasculitis despite normal laboratory findings. Symptoms resolved with supportive care, without documented renal involvement during follow-up.

A simulation of one US birth cohort projected more chronic hepatitis B infections under deferred or shared decision-making vaccination than universal birth-dose vaccination, with estimates dependent on coverage and transmission assumptions.

Australian adolescents who reported eating more fruit and drinking fewer sugar-sweetened beverages were less likely to cross depression or anxiety screening thresholds over three years, although the observational findings did not establish causality.

A consumer health explainer reviews hydration and blood pressure, including general beverage-intake estimates and cautions for heart failure and kidney disease. It identifies no established daily water target specifically for blood pressure control.