A primary care physician describes combining nutrition counseling, individualized monitoring, and pharmacotherapy in obesity care. The interview offers a practice philosophy rather than comparative evidence supporting one treatment strategy.

Four pending lawsuits challenge state-mandated physician collaboration or supervision requirements for advanced practice clinicians. Plaintiffs allege these arrangements impose unconstitutional financial and professional barriers, but courts have not resolved the claims.

New consensus guidance favors once-daily oral iron and simplified IV administration, including fewer test doses, premedications, and infusion visits. Several recommendations depart from established protocols and require formulation-specific clinical judgment.

In a prospective study of nearly 4,000 children evaluated for suspected pulmonary embolism, the PERC-Peds rule demonstrated 99.6% sensitivity and a 0.1% false-negative rate. The findings support diagnostic assessment performance in the study population without establishing broader implementation outcomes.

A systematic review and meta-analysis of studies involving more than 230,000 adolescents found that greater social jet lag was associated with higher anxiety levels. The findings identified a consistent but small association and did not establish causality.

Among 90 pediatric patients with relapsed or refractory B-cell precursor ALL, prior blinatumomab was associated with more relapses at atypical extramedullary sites. The retrospective single-center findings require prospective confirmation.