Because the patient was complaining of both chest discomfort and dyspnea–which can be caused by vomiting and dehydration–the clinician must consider a potential coronary etiology, even in a 38-year-old.

“The art now is to match the intensity of treatment to both global cardiovascular risk and the patient’s blood pressure, rather than chasing a number at all costs.” – Dr. Carolyn Lam, National Heart Center of Singapore

Reductions in lean body mass are likely concentrated in non-contractile components rather than reflecting a clear decline in muscle function.

“There is enormous exuberance about starting GLP-1 drugs, but not nearly enough attention to what happens when people stop.” – Senior study author Ziyad Al-Aly, MD; Washington University School of Medicine

The FDA notice added that a letter was sent out about the recall. However, it did not include a press release or other specific details.

“There is growing reason to believe [puberty blockers] are exacerbating the very dysphoria they are supposed to resolve and placing vulnerable children on a largely self-reinforcing path toward permanent transitions, often with serious and lasting physical consequences.” – Dr. Julia Mason