“Too many neurons go astray, and that’s when you get amyloid-beta production. And then it’s tau, and then it’s dead cells, then dementia — and then it’s too late.” — Jeffrey Savas, Northwestern University

“Disruption to the glymphatic system is likely to impair our ability to clear the brain of the amyloid and tau that causes Alzheimer’s disease.” — Hui Hong, University of Cambridge

Caregiver burden is common, cumulative, and often unspoken, manifesting as fatigue, depression, irritability, and social withdrawal.

“Fenebrutinib represents the first potential scientific breakthrough for the PPMS community in over a decade.” — Levi Garraway, MD, PhD, Roche Chief Medical Officer

“It’s not a case of cannabis being all good or all bad. It depends on how people are using it, what outcomes you’re looking at, what products are being used, for what reasons, and what part of the lifespan.” — Anika Guha, Ph.D., CU Anschutz

“For most patients in the early stages of schizophrenia, symptomatic remission can be achieved using a simple treatment algorithm comprising the sequential administration of amisulpride and clozapine.” — Leucht et al, J Clin Psychiatry 2026