As sedation and anesthesia for extensive tattooing draw greater attention, questions about credentialing, facility standards, prolonged procedures, local anesthetic toxicity, and regulatory oversight remain unsettled across practice settings.

As minimally invasive surgery increasingly defines training and practice, one surgeon argues that declining exposure to open procedures may leave younger surgeons less prepared to recognize when conversion is necessary.

In an adaptive randomized trial of adults with long COVID, fluvoxamine modestly reduced fatigue and improved quality-of-life scores through 90 days, while metformin findings remained inconclusive after dose modification and early termination.

Extensively drug-resistant Shigella has increased in US surveillance, with sexual transmission emerging as an important route among some populations. Rising multidrug resistance may complicate treatment, although many infections remain self-limited.

Across three cohorts, molecular patterns in human milk were associated with maternal nutritional status, mammary biological signatures, and infant growth. Seven candidate biomarkers emerged, but their clinical utility and the proposed vitamin B5 mechanism remain unproven.

In SCRaTCH-OFO, live birth rates were 64% with endometrial scratching and 57% without it among patients with unexplained infertility and favorable natural-conception prognosis. The difference was not statistically significant, and enrollment fell short.