Semaglutide use before or during pregnancy was associated with greater gestational weight gain and several adverse outcomes in a retrospective cohort, although similar findings among former users complicate attribution to direct fetal exposure.

An expert presentation at an obstetric ultrasound congress highlighted how real-time ultrasound guidance may improve the completeness and safety of early pregnancy procedures by maintaining instrument visualization and reducing procedural complications.

A large Danish registry study found that current use of oral menopausal hormone therapy was associated with increased venous thromboembolism risk, while transdermal therapy was not generally associated with higher thrombotic rates across regimens, doses, or durations.

Intrauterine mepivacaine administered shortly before IUD placement reduced procedural pain and improved patient-reported experience in a randomized trial of women receiving smaller-diameter IUDs, although comparisons with other analgesic approaches remain limited.

Fetal macrosomia showed the strongest association with shoulder dystocia in a single-center case-control study of vaginal deliveries. Maternal overweight and diabetes also contributed to risk, while the low event count and retrospective design limit prediction.

Testosterone prescribing for women has risen sharply despite the absence of FDA-approved female-specific products. The increase is occurring alongside pharmacy dispensing barriers and renewed regulatory attention, while guideline-supported use remains largely limited to hypoactive sexual desire disorder in postmenopausal women.