The study looks at outcomes of people who came down with COVID during the infection’s first wave. Fatigue, pain, and memory loss were the most common persistent symptoms, in that order.

Prior research showed that higher flavonol consumption was associated with lower Alzheimer’s risk. This longitudinal study demonstrated that increased flavonol consumption yielded slower declines in global cognition and in episodic, semantic, and working memory, independent of other health and lifestyle factors.

Pneumococcal vaccination guidelines for adults have been updated with the goal of preventing more invasive pneumococcal disease while also making the guidelines clearer and simpler to follow: Adults over 18 years of age who have not received a vaccine should be given an initial dose and a follow-up dose one year later. Those who previously received PCV13 should be given PPSV23 ideally, or PCV20 if the former is not available. Those who previously received PPSV23 may be given one dose of PCV20 or 15 after at least 1 year.

In comparison to 72% of patients who received placebo, 45% of those who received teplizumab-mzwv (Tzield, Provention Bio) over the course of a median follow-up of 51 months were found to have stage 3 type 1 diabetes. Teplizumab-mzwv appeared to delay the onset of type 1 diabetes by about two years, as the median time from randomization to diagnosis of stage 3 diabetes was 50 months in the teplizumab-mzwv group and 25 months in the placebo group.

The new Moderna bivalent vaccine showed higher antibody development vs BA.4/BA.5 than the original version and also showed activity (although lower) against the new BQ1.1 strain. The Pfizer-BioNTech bivalent vaccine generated 3- to 5-fold higher antibody levels than the original vaccine against BA.4/.5 and 11-fold higher levels vs the newer variants.

The shortage is driven by increased prescribing due to bacterial infection coexisting with RSV infection, and in cases where it is not possible to tell if the patient is experiencing a bacterial or viral URI. Substitute antibiotics to consider include cephalosporins and amoxicillin-clavulanate.