The American Gastroenterological Association issued nine best practice statements on colorectal and esophageal surveillance in older adults. Recommendations emphasize individualized decisions, life expectancy, treatment candidacy, procedural risks, and patient preferences.

The FDA approved tirzepatide to reduce major cardiovascular event risk in high-risk adults with type 2 diabetes. SURPASS-CVOT established noninferiority to dulaglutide rather than cardiovascular superiority.

Double-filtration plasmapheresis reduced circulating concentrations of several PFAS in small patient samples, while microplastic changes varied by polymer. The exploratory findings do not support apheresis for environmental pollutant removal.

Hospital ownership of health insurance plans increased from 18.3% in 2018 to 27.2% in 2023, with higher adoption among academic institutions. Effects on care, physician incentives, and costs remain uncertain.

A patient with advanced, treatment-resistant lung cancer experienced complete tumor disappearance after sodium selenite treatment and remained tumor-free for 10 years. The single case cannot establish efficacy, safety, or causality.

Two phase 3 trials found upadacitinib increased scalp, eyebrow, and eyelash regrowth in adolescents and adults with severe alopecia areata. Longer-term safety, durability, and regulatory review remain important considerations.