Articles related to Geriatrics

Hypertension was associated with osteoarthritis in a Korean population analysis and accelerated cartilage deterioration through vasopressin signaling in mouse models, identifying a potential disease pathway whose therapeutic relevance in humans remains unproven.

In a retrospective memory-clinic cohort, greater MRI-derived brain age was associated with dementia progression among patients with subjective cognitive decline, although its incremental predictive value was limited and external validation remains necessary.

The FDA has approved tavapadon, a selective D1/D5 dopamine receptor partial agonist, for adults with Parkinson disease following phase 3 studies demonstrating benefit both as monotherapy in early disease and as adjunctive therapy to levodopa.

Interviews with older adults living with dementia or mild cognitive impairment highlighted recurring communication gaps surrounding driving cessation, suggesting that earlier, structured discussions and transition planning may better support patients and families during a highly personal decision.

A systematic review of 12 studies found that vortioxetine consistently improved depressive symptoms in adults aged 65 years and older with major depressive disorder, but evidence for cognitive benefits remained mixed and largely confined to selected cognitive domains.

A Florida senior care organization reported identifying more dementia cases at earlier stages after replacing paper-based cognitive screening with a brief digital assessment, though independent diagnostic validation remains unavailable.