Articles related to Geriatrics

A BMJ systematic review of 69 trials found calcium and vitamin D supplementation provided little to no reduction in fracture or fall risk among nearly 154,000 older adults studied.

Menopausal hormone therapy users showed significantly higher bone mineral density at the spine and hip than non-users in a retrospective cohort of 387 postmenopausal women.

Frontal release sign positivity was associated with a 78% higher hazard of developing dementia among cognitively intact adults aged 70 and older in a longitudinal cohort study at a single academic Alzheimer’s research center.

Glucosamine use was associated with a 25% increase in mortality risk in patients with Alzheimer’s disease-related dementia in a retrospective analysis of more than 50,000 patients, with no corresponding signal observed in those with mild cognitive impairment.

A 509,926-patient Medicare cohort found that recombinant herpes zoster vaccination was associated with a 5.8 percentage point reduction in 4-year dementia risk among older adults following skilled-nursing facility admission, adding to a growing body of observational evidence linking RZV to cognitive protection.

A Medicare cohort study found a median delay of 494 days between incident heart failure diagnosis and ATTR-CM diagnosis, with female sex, aortic stenosis, COPD, coronary artery disease, diabetes, and hypertension associated with longer diagnostic delays.