Articles related to MEDICAL DIAGNOSTICS

A randomized noninferiority trial involving 648 men with MRI-visible prostate lesions found that cognitive fusion biopsy achieved clinically significant prostate cancer detection rates similar to software-based fusion biopsy. Subgroup analyses suggested body mass index may influence the relative performance of each approach.

AI-enabled retinal imaging platforms are being deployed across healthcare settings to identify ocular and systemic disease signals, though the role of these technologies continues to evolve alongside regulatory approvals and clinical validation.

A plasma p-tau217/Aβ42 ratio accurately identified amyloid-PET positivity in older veterans without traumatic brain injury, but diagnostic performance declined substantially among those with a history of TBI, particularly following more severe injuries.

A man in his early 30s presenting with post-viral chest pain and bilateral forearm numbness posed a diagnostic challenge when automated ECG interpretation missed findings later consistent with acute pericarditis, including diffuse concave-upward ST elevation, PR depression, and a positive Spodick sign.

A Cureus case report describes complete fecaloma resolution after two 1 L Classic Coca-Cola enemas in an 82-year-old woman with dementia whose impaction failed conservative management.

OCT angiography revealed subclinical retinal and choroidal blood flow changes that correlated with disease severity across diabetic retinopathy, AMD, and central serous retinopathy in cited studies.