Articles related to RISK STRATIFICATION

Premature menopause was linked to a 40% higher long-term risk of coronary heart disease in a pooled analysis of more than 10,000 women followed across six cohort studies.

A Bayesian network meta-analysis of 31 randomized trials found aerobic, combined, and high-intensity interval training each associated with reductions in 24-hour ambulatory systolic blood pressure compared with control conditions, with no modality demonstrating clear superiority and all comparisons rated very low to low confidence.

Right coronary artery stenosis was associated with the highest adjusted risk for sudden cardiac death across a 22,495-patient Finnish angiography registry, with a hazard ratio of 1.53 after accounting for concomitant stenoses and revascularization strategy.

A Medicare cohort study found a median delay of 494 days between incident heart failure diagnosis and ATTR-CM diagnosis, with female sex, aortic stenosis, COPD, coronary artery disease, diabetes, and hypertension associated with longer diagnostic delays.

Accelerometer-derived sleep-wake cycle metrics independently predicted incident dementia in 53,448 UK Biobank participants, with predictive improvement comparable to APOE genotype contribution when added to age-only models.

Baseline cognitive performance predicted future depression risk in opposite directions depending on depression history: lower cognition signaled higher risk in never-depressed controls, while higher cognition was associated with greater relapse risk in remitted depression, in a longitudinal UK Biobank analysis of 3,724 participants.