Articles related to COHORT STUDY

Women with Parkinson disease exhibited greater Alzheimer-related amyloid plaque burden than men in an autopsy-confirmed cohort, although cognitive performance and dementia rates were similar between sexes.

Short-term benzodiazepine use after mass trauma was not associated with increased 12-month PTSD risk in a large retrospective cohort. Persistent use showed a different pattern, and the observational findings did not establish causality.

A Medicare cohort study found a median delay of 494 days between incident heart failure diagnosis and ATTR-CM diagnosis, with female sex, aortic stenosis, COPD, coronary artery disease, diabetes, and hypertension associated with longer diagnostic delays.

Baseline cognitive performance predicted future depression risk in opposite directions depending on depression history: lower cognition signaled higher risk in never-depressed controls, while higher cognition was associated with greater relapse risk in remitted depression, in a longitudinal UK Biobank analysis of 3,724 participants.

Antidepressant prescription trajectories remained stable or absent for the majority of Swedish adults who continued working past age 65, with no worsening pattern observed around work exit in a 10-year longitudinal cohort of 32,849 participants.

An observational study of 17,088 UK Biobank participants found that substantial cardiovascular risk reduction required 560–610 minutes of moderate to vigorous physical activity per week, roughly three to four times current public health recommendations.