Articles related to COHORT STUDY

Two prospective cohorts found that metabolically unhealthy adults generally had higher dementia risk estimates regardless of obesity status. Metabolically healthy obesity was not associated with increased dementia risk in primary analyses, though findings varied across sensitivity analyses.

A Swedish register-based cohort associated GLP-1 receptor agonist use with higher relative risk of anterior ischemic optic neuropathy. Absolute event rates were low, and findings attenuated after diabetes-severity controls.

Video-based ADHD prescribing increased substantially following Australia’s permanent telehealth reforms, with ADHD consultations showing greater virtual adoption than other psychotropic prescribing categories. Observational findings describe utilization patterns but do not establish causality.

Filtered coffee consumption was associated with lower biological age-acceleration measures in nearly 50,000 UK Biobank participants, while instant coffee showed the opposite pattern. The cross-sectional analysis did not establish causality and remains hypothesis-generating.

A large ECHO Cohort analysis associated several pregnancy urinary chemical biomarkers with modest shifts in gestational age and fetal growth measures. The observational findings did not establish causality.

Objective sleep measurements from nearly 61,000 adults linked greater sleep regularity with lower all-cause, cancer, and cardiometabolic mortality risk. Sleep regularity outperformed sleep duration in mortality prediction models.