Articles related to Psychology

The FDA granted Breakthrough Therapy designation to DT120, an oral lysergide formulation under investigation for major depressive disorder, based on phase 3 findings suggesting rapid and sustained antidepressant effects, though the treatment remains investigational and unapproved.

Baseline activity in the left dorsolateral prefrontal cortex and right precuneus during working memory and emotion-regulation tasks was associated with depression severity one year later in young adults at elevated risk for affective disorders, but not with future mania symptoms.

Prior ayahuasca experience was associated with lower self-reported depression, stress, and alcohol use among Brazilian ceremony participants, while also correlating with stronger spiritual wellbeing and metaphysical beliefs in an observational study that did not establish causality.

An expert commentary argues that persistent physical symptoms should be approached through a balanced framework that validates patient suffering, excludes dangerous medical illness, and incorporates evidence-informed understanding of brain-body mechanisms without dismissing symptoms as psychological.

Childhood ADHD was associated with higher rates of adult psychiatric and neurologic hospitalization in a Finnish birth cohort followed into adulthood, while most somatic health outcomes showed little evidence of a sustained association.

Testimony from a psychiatrist in the Lindsay Clancy murder trial has highlighted how clinical documentation, incomplete information, and retrospective interpretation of psychiatric records can become central evidence in legal proceedings without resolving underlying questions of diagnosis or criminal responsibility.