Articles related to AUTISM SPECTRUM DISORDERS (ASD)

Analysis of genetic testing data from nearly 180,000 individuals with autism suggests that Phelan-McDermid syndrome may affect approximately 1 in 7,300 people. The findings indicate the condition may be substantially more common than previously estimated and highlight ongoing diagnostic gaps.

Youth with ADHD and comorbid ASD showed distinct medication patterns and greater psychiatric burden in a large EHR cohort. The observational findings did not establish causal treatment effects.

Single-nucleus multi-omics sequencing across genetically diverse ASD mouse models revealed convergent molecular and cellular changes in early brain development, despite distinct underlying mutations.

Approach-withdrawal behavioral patterns — including dysregulated negative affect and resistance to routine change — showed moderate associations with co-occurring internalizing and externalizing symptoms in a cohort of 280 children with autism.

Prenatal exposure to medications that inhibit sterol biosynthesis was associated with higher rates of autism spectrum disorder diagnosis in a 6.14-million-record retrospective analysis.

“There are a lot of people with autism who don’t have a folate deficiency, and there are a lot of people with a folate deficiency who don’t have autism.” — Ben Rein, PhD