Articles related to Allergy & Immunology

Allergy testing in asthma is most useful when results could change management, with clinical history guiding targeted sensitization testing and total IgE serving a limited role outside anti-IgE biologic assessment.

The GINA 2026 update introduces age-stratified primary care flowcharts for asthma exacerbation management, expands biologic guidance including depemokimab, and adds a formal red-flag list for fatal or near-fatal asthma risk in adults and adolescents.

A DNA methylation–based IgE score measured in infancy was associated with recurrent wheezing by age 3 across three pediatric cohorts.

A small prospective study suggests inferior turbinate reduction may offer greater short‑term symptom relief than continued medical therapy in children with refractory allergic rhinitis, though evidence remains limited.

Investigators surmised that current influenza vaccination programs provide substantial protection but could be further improved by strategies that could mitigate repeat vaccination effects.

The working group strongly recommended inhaled corticosteroids (ICS) and streamlined management of asthma by suggesting a combination of ICS and rapid-onset long-acting β-agonist as both reliever and controller agents and step-up therapy by increasing ICS and/or adding long-acting anticholinergic agents.