Articles related to ALLERGIES
ACIP: Updated Vaccine Guidance for the 2023-2024 Influenza Season
Physicians should encourage all patients 6 months of age and older to get vaccinated against influenza this season, regardless of egg allergy. The ACIP’s updated guidance is based on the latest scientific evidence and is designed to help protect patients from influenza.
Allergy & Immunology August 31st 2023
Phase 3 Trial of Epicutaneous Immunotherapy in Toddlers with Peanut Allergy
A phase 3, multicenter, double-blind, randomized, placebo-controlled trial was conducted to evaluate the efficacy and safety of epicutaneous immunotherapy with a peanut patch in children aged 1 to 3 years with peanut allergy. No approved treatment for peanut allergy exists for children under 4 years old. Participants with confirmed peanut allergy were assigned to either receive the peanut patch or a placebo daily for 12 months. The primary endpoint was the treatment response measured by the eliciting dose of peanut protein at 12 months. The trial showed that 67.0% of children in the intervention group demonstrated a treatment response compared to 33.5% in the placebo group. Adverse events occurred in both groups, with serious adverse events and anaphylaxis observed more frequently in the intervention group. However, serious treatment-related adverse events were rare. In conclusion, this trial demonstrated that epicutaneous immunotherapy with a peanut patch for 12 months was more effective than placebo in desensitizing children aged 1 to 3 years with peanut allergy and increasing their tolerance to peanut protein. Although adverse events were observed in both groups, serious treatment-related adverse events were uncommon. These findings suggest that epicutaneous immunotherapy may be a potential treatment option for young children with […]
Allergy & Immunology May 18th 2023
Maternal Diet During Pregnancy May Impact Development of Asthma, Allergies in Offspring
At the American Academy of Allergy, Asthma & Immunology (AAAAI) annual meeting, Carina Venter, PhD, associate professor of pediatrics at Children’s Hospital Colorado and the University of Colorado Denver School of Medicine, provided the latest data on the role that maternal diet during pregnancy may have on the infant microbiome and the subsequent development of allergies and asthma. The findings are that eating plenty of vegetables and limited fried, low-fiber, and sugary foods may prevent asthma and allergies in unborn children.
Allergy & Immunology March 8th 2022
Acute Allergic Reactions to mRNA COVID-19 Vaccines
Anaphylaxis to the mRNA COVID-19 vaccines is currently estimated to occur in 2.5 to 11.1 cases per million doses, largely in individuals with a history of allergy. In this JAMA “Research Letter”, the authors investigated acute allergic reaction incidence with more than 60,000 mRNA COVID-19 vaccine administrations at Mass General Brigham (MGB).
Allergy & Immunology March 16th 2021