Articles related to Pain Medicine

Updated AAN and AHS guidance outlines when to initiate preventive migraine therapy, how to select treatments based on efficacy and tolerability, and how to tailor management for special populations and comorbidities.

This review outlines a practical approach to headache imaging, emphasizing that MRI is preferred over CT in most nonemergent settings, while contrast-enhanced MRI should be reserved for specific red-flag scenarios such as malignancy, immunosuppression, focal neurologic deficits, intracranial pressure disorders, infection, and trigeminal autonomic cephalalgias.

U.S. News expanded its 2026-2027 hospital rankings with new regional specialty evaluations in cancer and cardiovascular care while increasing recognition for regional hospitals. Rankings continued to emphasize risk-adjusted mortality, preventable complications, patient experience, and objective outcomes measures.

A genome-wide analysis of more than 2.5 million adults identified 26 genetic regions associated with fibromyalgia risk. The findings support a neurologic biological basis for the condition, though they do not establish causality or create a diagnostic test.

An observational study associated repeated gabapentin prescribing with higher rates of dementia and mild cognitive impairment, particularly among adults aged 18 to 64 years. Experts emphasized that the findings do not establish causality and should be interpreted cautiously.

Multimodal MRI analysis identified two distinct migraine subgroups in a 111-patient cohort, with one cluster showing widespread cortical-subcortical connectivity changes and lower cortical volumes tied to greater disease burden and disability.