Articles related to Pain Medicine

Multimodal MRI analysis identified two distinct migraine subgroups in a 111-patient cohort, with one cluster showing widespread cortical-subcortical connectivity changes and lower cortical volumes tied to greater disease burden and disability.

A systematic review of 43 randomized controlled trials found high-certainty evidence that multiple CGRP-targeted therapies reduced monthly migraine headache days by approximately 2 days versus placebo in adults with chronic migraine.

A 21-element enhanced recovery protocol implemented across 18 US hospitals reduced inpatient opioid use by 56% in children undergoing GI surgery, with patients receiving 13 or more protocol elements averaging one fewer hospital day and half the complication risk.

Opioid prescribing for cancer patients reporting no pain declined substantially across a single Connecticut health system from 2016 to 2020, while prescribing for patients reporting pain remained stable.

A qualitative study of 169 Colorado adults aged 60 and older found most preferred combination THC-CBD edible products over single-cannabinoid options when seeking relief from pain, sleep, and mood symptoms.

Brain glucose levels regulated oligodendrocyte progenitor cell proliferation and maturation in mouse and cell models, with ketone bodies restoring myelin production when glucose use was disabled.