Articles related to Surgery, Orthopedic
Tymlos Approved for Men with Osteoporosis at High Risk for Fracture
Clinical trials of abaloparatide, a human parathyroid hormone related peptide analog, showed significantly increased bone mineral density at 12 months in the lumbar spine and femoral neck in men with osteoporosis.
Clinical Pharmacology January 30th 2023
Perioperative Gabapentin Increases Adverse Clinical Events in Older Adults
According to the findings of the study, gabapentin should not be used on a regular basis. Individualization is required, based on the type of pain and the risk of delirium. If gabapentin is used to control postoperative pain, it must be closely monitored for the development of delirium. Low-dose opioids, along with nonpharmacologic pain management strategies such as postoperative physical therapy and mobilization, can still be used safely in the study population. Rather than relying on a single medication, a more holistic approach to postoperative pain control in the hospital setting is required.
Anesthesiology January 30th 2023
Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis After a Fracture
In this study, more than 12,000 patients 18 years and older with hospitalization for extremity fracture were randomized to LWMH or aspirin. Rates of DVT were 1.7% and 2.5%, respectively. PE, bleeding complications, and other SAEs were similar across groups. Death occurred in 0.73% and 0.78% respectively for LWMH and aspirin.
Hematology January 25th 2023
3 Physical Exam Pearls for Patients with Pain
Use of Carnett sign, greater trochanter palpation, and a simple extension to typical joint examination can reduce imaging and orthopedic referrals by primary care physicians and bring faster effective treatment to the patient.
Family Medicine/General Practice January 19th 2023
Effect of Diet and Exercise on Knee Pain in Patients with Osteoarthritis and Overweight or Obesity
In a study of more than 800 rural-living men and women with knee osteoarthritis, an 18-month program of diet and exercise versus attention control yielded an average 14-pound greater weight loss in the test group – but not much difference in pain magnitude.
Family Medicine/General Practice January 5th 2023