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Annals of Internal Medicine
A 12-month controlled trial randomized 189 individuals to spend 70–90 minutes performing 11 exercises or 20–30 minutes performing 5 exercises for 3 months. Outcomes were measured biweekly for the intervention period and again at 6 and 12 months. The two approaches were similar, except for one outcome. In the Knee Injury and Osteoarthritis Outcome Score for function in sports and recreation, high-dose therapy was superior.
Family Medicine/General Practice February 8th 2023
Medical Professionals Reference (MPR)
Clinical trials of abaloparatide, a human parathyroid hormone related peptide analog, showed significantly increased bone mineral density at 12 months in the lumbar spine and femoral neck in men with osteoporosis.
Clinical Pharmacology January 30th 2023
Pharmacy Practice News
According to the findings of the study, gabapentin should not be used on a regular basis. Individualization is required, based on the type of pain and the risk of delirium. If gabapentin is used to control postoperative pain, it must be closely monitored for the development of delirium. Low-dose opioids, along with nonpharmacologic pain management strategies such as postoperative physical therapy and mobilization, can still be used safely in the study population. Rather than relying on a single medication, a more holistic approach to postoperative pain control in the hospital setting is required.
Anesthesiology January 30th 2023
ACP Internist
Use of Carnett sign, greater trochanter palpation, and a simple extension to typical joint examination can reduce imaging and orthopedic referrals by primary care physicians and bring faster effective treatment to the patient.
Family Medicine/General Practice January 19th 2023
JAMA Network
In a study of more than 800 rural-living men and women with knee osteoarthritis, an 18-month program of diet and exercise versus attention control yielded an average 14-pound greater weight loss in the test group – but not much difference in pain magnitude.
Family Medicine/General Practice January 5th 2023
Gabapentin has been increasingly used as part of a multimodal analgesia regimen to reduce opioid use in perioperative pain management. In this cohort study of 237,872 adults aged 65 years or older, perioperative gabapentin users had significantly increased risk of delirium, new antipsychotic use, and pneumonia compared with nonusers after major surgery.
Anesthesiology October 3rd 2022