Articles related to Hepatology
Capsule Endoscopy in Gastrointestinal Disease: Evaluation, Diagnosis, and Treatment
Capsule endoscopy, also known as wireless capsule endoscopy or video capsule endoscopy, is a noninvasive procedure that uses a swallowed capsule-shaped miniature camera for direct visual and diagnostic evaluation of various gastrointestinal (GI) diseases. Although originally intended as a tool to examine the small intestine, which is mostly beyond the reach of conventional endoscopy, capsule endoscopy is now being used to examine the entire length of the GI tract.
Gastroenterology May 3rd 2022
Mortality and Morbidity in Mild Primary Hyperparathyroidism: Results From a 10-Year Prospective Randomized Controlled Trial of Parathyroidectomy Versus Observation
Primary hyperparathyroidism (PHPT) is associated with increased risk for fractures, cardiovascular disease, kidney disease, and cancer, along with increased mortality. In mild PHPT with modest hypercalcemia and without known morbidities, parathyroidectomy is debated because no long-term randomized trials have been performed related to it.
Cardiology April 27th 2022
Treatment Approaches for Advanced Hepatocellular Carcinoma: Insight From the 2022 Gastrointestinal Cancers Symposium
A potentially practice-changing clinical trial for first line therapy is the first to show that the combination of two immunotherapy medications is an effective treatment for hepatocellular carcinoma (HCC). The HIMALAYA study evaluated combination immunotherapy (IO-IO), durvalumab with tremelimumab, as frontline therapy in patients with unresectable HCC. Overall survival was significantly improved with the IO-IO combination compared with sorafenib monotherapy (16.4 vs 13.8 months; hazard ratio [HR], 0.78; 96% CI, 0.65-0.92; P =.0035). Early results of the phase three LAUNCH trial are also promising. This trial compared the combination of lenvatinib with transarterial chemoembolization (TACE) to lenvatinib alone in an Asian population with advanced HCC. The lenvatinib-TACE group achieved a higher median overall survival (17.8 vs. 11.5 months and median progression-free survival (10.6 vs. 6.4 months). Muhammad Shaalan Beg, MD, director for GI Medical Oncology at UT Southwestern Medical Center in Dallas summarizes these and other takeaways from emerging research on advanced HCC presented at the recent ASCO GI Symposium.
Gastroenterology March 1st 2022
Elderly Man Presents With Bradycardia and Chronic Kidney Dysfunction
An interesting case study in BRASH (bradycardia, renal failure, atrioventricular blockade, shock, and hyperkalemia) syndrome highlights Rare Disease Day, which took place on 2/28/22. After reviewing the patient’s history and symptoms, would you agree on the diagnosis?
Cardiology March 1st 2022
9 Volunteer Opportunities for Doctors
From the American Red Cross to volunteering overseas, there are plenty of feel-good “enlistments” out there for the practicing or retired physician, which can help ward off boredom and burnout while adding the benefit of perhaps learning a new skill or meeting new people. Whether your goals are short-term or you’re in for the long haul, here are nine opportunities to help humanity and feel good about the part you’re playing in the world.
Allergy & Immunology December 20th 2021