Articles related to Hepatology

The TOPAZ-1 trial demonstrates that adding durvalumab to standard chemotherapy significantly improves overall survival in patients with advanced biliary tract cancer, potentially establishing a new first-line treatment option for this difficult-to-treat malignancy.

An estimated 5% of U.S. adults have consumed at least one potentially hepatotoxic herbal supplement in the past month, raising concerns about liver health risks associated with unregulated botanical products.

Emerging data suggest that lactated Ringer’s is associated with improved health outcomes and may be superior to normal saline in acute pancreatitis management.

Liver injuries tied to botanical supplements are on the rise, with cases nearly tripling in a decade. Healthcare providers should be aware of this growing concern and its implications for patient care.

In patients with both cirrhosis and atrial fibrillation, apixaban initiation was associated with lower rates of major bleeding compared to rivaroxaban or warfarin, without compromising thromboembolic protection.

Despite its theoretical benefits, IV albumin has not shown consistent superiority over crystalloid solutions in sepsis management, prompting a reevaluation of fluid resuscitation strategies in critical care settings.