Articles related to METABOLIC HEALTH

Two prospective cohorts found that metabolically unhealthy adults generally had higher dementia risk estimates regardless of obesity status. Metabolically healthy obesity was not associated with increased dementia risk in primary analyses, though findings varied across sensitivity analyses.

A prototype wearable ring continuously monitored multiple sweat biomarkers, including glucose and ketones, in healthy volunteers and individuals with type 1 diabetes. The device’s readings tracked established monitoring technologies, though larger validation studies remain necessary.

Filtered coffee consumption was associated with lower biological age-acceleration measures in nearly 50,000 UK Biobank participants, while instant coffee showed the opposite pattern. The cross-sectional analysis did not establish causality and remains hypothesis-generating.

A national analysis found that clinical obesity was present in more than one-quarter of adults with normal BMI values. The findings highlight limitations of BMI alone for identifying excess adiposity and obesity-related health risk.

A new analytical framework applied to 30,000+ parent-child trios found that uninherited parental genes shape children’s height, BMI, and academic performance to a degree approaching the influence of children’s own DNA.

A retrospective analysis of more than 840,000 patients with breast cancer found lower all-cause mortality and reduced recurrence risk among those with obesity or type 2 diabetes who received GLP-1 receptor agonists compared with similar patients who did not, though the study did not establish causation.