Articles related to Neurology

High-dose vitamin D demonstrated a 34% reduced risk of disease activity in both CIS and early RRMS patients, with MRI markers showing particular improvement, though no significant impact on clinical symptoms or disability progression was observed.

Brain aging follows distinct stages with metabolic dysregulation beginning decades before symptoms appear, creating an opportunity for preventive intervention rather than reactive treatment.

Treatment with gantenerumab for approximately eight years reduced the risk of developing symptoms from essentially 100% to about 50% in participants with genetic mutations causing early-onset Alzheimer’s.

Methylene blue’s ability to penetrate the blood-brain barrier while reducing oxidative stress and promoting Nrf2 expression presents a novel therapeutic pathway for neurodegenerative disorders that warrants further investigation despite limited clinical evidence.

“We’ve published several editorials in this past year focused on a 1-year fellowship in a specialty that arguably needs way, way more time, more than 1 year. Are we doing our trainees or even our patients a disservice by continuing that 1-year construct, which is now solidly 30 years old?”

Up to 45% of people in the US experience fatigue, making medication-induced drowsiness a significant clinical consideration when prescribing commonly used drug classes.