Articles related to NEURODEGENERATIVE DISEASES

Frontal tau accumulation was associated with disrupted deep-sleep slow waves and poorer episodic memory performance in older adults, offering a potential physiological link between Alzheimer’s-related pathology and age-related memory decline.

A 10-year retrospective cohort study associated glaucoma with higher risks of Alzheimer disease, vascular dementia, and other neurodegenerative diagnoses, although administrative coding and surveillance bias limit causal interpretation.

Women with Parkinson disease exhibited greater Alzheimer-related amyloid plaque burden than men in an autopsy-confirmed cohort, although cognitive performance and dementia rates were similar between sexes.

BCG vaccination increased immune responsiveness without inflammatory activation and shifted beta-amyloid patterns in a small mechanistic study of older adults.

Frontal release sign positivity was associated with a 78% higher hazard of developing dementia among cognitively intact adults aged 70 and older in a longitudinal cohort study at a single academic Alzheimer’s research center.

Survey responses from 5,797 Fox Insight participants suggest sleep disturbances, autonomic dysfunction, and emotional changes preceded Parkinson’s disease diagnosis by more than a decade in a substantial proportion of respondents.