Articles related to RISK FACTORS

In a prospective cohort of more than 112,000 French adults, higher intake of several commonly used food preservatives was associated with increased risks of hypertension and cardiovascular disease, though the observational design cannot determine whether the additives themselves caused the observed outcomes.

In a secondary analysis of 371,038 U.S. adults, individuals reporting several cardiovascular disease (CVD) risk factors or established CVD reported less frequent whole-fruit consumption. The cross-sectional survey identified associations only and did not establish whether dietary behaviors preceded disease.

A multicenter analysis of adults with biopsy-confirmed MASLD found that roughly one-quarter of cirrhosis cases developed before age 50, with type 2 diabetes and genetic susceptibility associated with earlier progression.

A large Danish registry study found that current use of oral menopausal hormone therapy was associated with increased venous thromboembolism risk, while transdermal therapy was not generally associated with higher thrombotic rates across regimens, doses, or durations.

Fetal macrosomia showed the strongest association with shoulder dystocia in a single-center case-control study of vaginal deliveries. Maternal overweight and diabetes also contributed to risk, while the low event count and retrospective design limit prediction.

Higher circulating xylitol levels were associated with increased rates of major adverse cardiovascular events in two large population cohorts, although the observational findings do not establish that xylitol directly causes cardiovascular harm.