Articles related to RISK FACTORS

An observational study of 17,088 UK Biobank participants found that substantial cardiovascular risk reduction required 560–610 minutes of moderate to vigorous physical activity per week, roughly three to four times current public health recommendations.

Daily peppermint oil supplementation was associated with reduced systolic blood pressure and resting heart rate in a small placebo-controlled trial of adults with elevated or stage 1 hypertension.

A retinal specialist reviewing GLP-1 ocular safety evidence at the Retina World Congress concluded that current data do not support withholding therapy based on ocular risk alone, while recommending baseline retinal examination and closer monitoring in patients with preexisting severe diabetic retinopathy.

A retrospective cohort study of 349,168 propensity-matched patients with diabetes found a hazard ratio of 2.22 for nonarteritic anterior ischemic optic neuropathy among semaglutide users compared with non-GLP-1 RA antidiabetic therapy users, with elevated risk emerging at two years and persisting through four years of follow-up.

A Swedish national cohort analysis linked bereavement to elevated incident cardiovascular disease risk before and during the COVID-19 pandemic, with the strongest pandemic-period association following partner loss.

Retrospective analysis of pediatric cancer survivors identified low overall CHIP prevalence, with antimetabolite therapy and methotrexate exposure emerging as the strongest treatment-associated signals.