Articles related to ALZHEIMER'S/DEMENTIA

A menopause-associated blood protein pattern was linked to poorer cognition and Alzheimer’s disease in older women across observational cohorts. Replication supports research interest, but the findings do not establish causality, individual prediction, or hormone-therapy prevention benefits.

In a retrospective memory-clinic cohort, greater MRI-derived brain age was associated with dementia progression among patients with subjective cognitive decline, although its incremental predictive value was limited and external validation remains necessary.

Interviews with older adults living with dementia or mild cognitive impairment highlighted recurring communication gaps surrounding driving cessation, suggesting that earlier, structured discussions and transition planning may better support patients and families during a highly personal decision.

A Florida senior care organization reported identifying more dementia cases at earlier stages after replacing paper-based cognitive screening with a brief digital assessment, though independent diagnostic validation remains unavailable.

Frontal tau accumulation was associated with disrupted deep-sleep slow waves and poorer episodic memory performance in older adults, offering a potential physiological link between Alzheimer’s-related pathology and age-related memory decline.

In a propensity-matched analysis of more than 66,000 adults with hypertension, blood-brain barrier (BBB)-crossing antihypertensives were associated with a 16% lower dementia risk than BBB-non-crossing agents. The observational design prevents causal conclusions but adds to growing interest in whether some antihypertensives may influence cognitive outcomes beyond blood pressure control.