Articles related to ALZHEIMER'S/DEMENTIA

A 9-member Delphi panel just issued 65 implementation recommendations for anti-amyloid mAbs in private practice. Here’s what counts as practice-shaping and what’s still consensus opinion.

Chronic PPI use was associated with elevated dementia and mild cognitive impairment risk in older adults across pooled observational studies, though high heterogeneity and residual confounding leave causality unresolved.

Researchers are increasingly studying peripheral biomarkers in high-risk populations to improve diagnosis and prediction, with standard therapies currently limited to temporary symptom relief.

Among the people who ate the least meat, the ones with the APOE 3/4 and 4/4 variants had over twice the risk of dementia than those who did not have these variants.

The reseachers acknowledge that the Delphi approach favors compounds already studied and may exclude agents identifiable only through high-throughput screening.

“Too many neurons go astray, and that’s when you get amyloid-beta production. And then it’s tau, and then it’s dead cells, then dementia — and then it’s too late.” — Jeffrey Savas, Northwestern University