Articles related to Psychiatry

Psychological menopause symptoms were associated with greater intention to leave employment in a Japanese cross-sectional study of more than 1,600 working women. Conference-reported findings do not establish causality or document actual workforce departures.

Experimental research linked alcohol exposure with microglia-mediated disruption of the brain’s extracellular matrix and subsequent neuronal dysfunction, identifying a neuroimmune mechanism that was also accompanied by extracellular-matrix abnormalities in human tissue samples.

LGBTQ+ physicians may face additional burnout-related stressors associated with workplace discrimination, microaggressions, and exclusion, highlighting the potential role of inclusive organizational cultures and supportive professional resources in physician well-being.

Biobehavioral markers previously linked to antidepressant response identified patients with major depressive disorder who were more likely to respond to sertraline or bupropion, although biomarker-guided treatment assignment did not significantly improve outcomes in a prospective validation trial.

Women with bulimia nervosa demonstrated smaller total cortical surface area and reduced nucleus accumbens volume compared with healthy controls in a large international neuroimaging study, with more frequent binge-eating episodes associated with additional structural differences across brain regions involved in reward, cognitive control, and interoception.

First-trimester benzodiazepine exposure was not associated with a meaningful increase in major congenital malformations in a large US cohort study, although findings related to coexposure with other psychoactive medications remained inconsistent and require further investigation.