Articles related to CHILD & ADOLESCENT PSYCHIATRY

Creatine supplementation showed mixed effects on depressive symptoms across five randomized trials involving patients with mood disorders. The early findings suggest potential adjunctive benefit in some populations but do not establish a consistent treatment effect.

Youth with ADHD and comorbid ASD showed distinct medication patterns and greater psychiatric burden in a large EHR cohort. The observational findings did not establish causal treatment effects.

Single-nucleus multi-omics sequencing across genetically diverse ASD mouse models revealed convergent molecular and cellular changes in early brain development, despite distinct underlying mutations.

Suicide mortality increased among adolescents and young adults across the Americas from 2000 to 2021. Rates varied by age, sex, and region, with widening disparities observed in population-level data.

Sleep midpoint variability, duration variability, and social jetlag were each associated with lower receptive vocabulary and visuospatial memory scores in 379 preschool-age children, with executive attention unaffected by any sleep regularity measure.

Approach-withdrawal behavioral patterns — including dysregulated negative affect and resistance to routine change — showed moderate associations with co-occurring internalizing and externalizing symptoms in a cohort of 280 children with autism.