Articles related to PSYCHOSIS

A narrative review and accompanying expert commentary outlined diagnostic features distinguishing substance-induced psychosis from primary psychotic disorders amid rising cannabis and stimulant exposure.

A meta-analysis of 285 studies found lifetime psychosis in over half of patients with bipolar disorder and comorbid schizophrenia in 8%, with substantial differences between bipolar I and bipolar II subtypes.

Caregiver burden is common, cumulative, and often unspoken, manifesting as fatigue, depression, irritability, and social withdrawal.

Although not remarkably high, a 2.8% development of psychotic symptoms represents a nonnegligible figure and lends further meta-analytic support to the 2007 FDA change in the drug label for stimulants.

“Nothing in her growing-up years could have prepared us for the shock and devastation of seeing this normal, happy child become totally incapacitated by schizophrenia.”

The study found that frequent use of high-potency cannabis is associated with changes in genes related to mitochondrial and immune function, particularly affecting the CAVIN1 gene.