Articles related to EVIDENCE REVIEW

A narrative review of studies from 1974 to 2025 described testosterone activity across musculoskeletal, metabolic, cardiovascular, and neurological systems in women, with evidence strength varying by domain.

Intensive blood-pressure lowering reduced major cardiovascular events similarly in adults with and without chronic kidney disease, without increasing kidney failure risk, although sustained declines in estimated glomerular filtration rate occurred more frequently.

A growing body of observational evidence links coffee consumption with lower risks of several cancers, particularly hepatocellular and endometrial cancer, but experts caution that current data do not justify prescribing coffee as a cancer-prevention strategy.

A review of prematurity-associated lung disease (PLD) argues that respiratory follow-up should extend beyond early childhood and focus on current symptoms and lung-function trajectories rather than relying exclusively on a history of bronchopulmonary dysplasia (BPD).

Gliomas and ependymomas appear to reuse developmental hierarchies, progenitor states, and neural-circuit signals that shape tumor heterogeneity and treatment response, although many proposed therapeutic vulnerabilities remain supported primarily by preclinical evidence.

A scoping review of 23 studies found that nurses most often implemented non-pharmacological postoperative pain interventions but participated less frequently in planning. Wide variation in interventions and outcomes limits conclusions about effectiveness or preferred approaches.