Articles related to TESTOSTERONE

A narrative review of studies from 1974 to 2025 described testosterone activity across musculoskeletal, metabolic, cardiovascular, and neurological systems in women, with evidence strength varying by domain.

Continued anabolic-androgenic steroid use was associated with persistent left ventricular hypertrophy and dysfunction, while discontinuation accompanied improved cardiac structure and systolic function. Small, nonrandomized subgroups limit conclusions about reversibility and treatment effects.

Testosterone prescribing for women has risen sharply despite the absence of FDA-approved female-specific products. The increase is occurring alongside pharmacy dispensing barriers and renewed regulatory attention, while guideline-supported use remains largely limited to hypoactive sexual desire disorder in postmenopausal women.

The Department of Defense announced annual testosterone-deficiency screening for service members aged 30 years and older, with optional testing for younger personnel. Clinicians have questioned whether broad population screening aligns with established diagnostic recommendations for hypogonadism.

“The FDA is failing women by denying access to a hormone their bodies naturally produce.” — Kelly Casperson, MD

Lower baseline testosterone and hormonal imbalances, including low SHBG and DHT levels, are significantly associated with increased all-cause and cardiovascular mortality in aging men.