Articles related to GENDER DISPARITIES

In a specialty-clinic cohort of 2,329 adults with Neuro-PASC, females reported more neurologic symptoms, greater fatigue, and, among nonhospitalized patients, poorer attention than males approximately 16 months after symptom onset.

Female mice recovering from a single ketamine exposure demonstrated microglia-driven neuroplasticity through FKBP51 activation, while male mice did not. The findings identify a sex-specific biologic pathway in a preclinical model, and human relevance remains unconfirmed.

Women with Parkinson disease exhibited greater Alzheimer-related amyloid plaque burden than men in an autopsy-confirmed cohort, although cognitive performance and dementia rates were similar between sexes.

After 23 years, men offered once-only sigmoidoscopy had 1.7 fewer colorectal cancers and 0.8 fewer CRC deaths per 100. In women, the mortality benefit didn’t reach significance.

“The amygdala’s response to social threat appears to feed into depressive symptoms much more strongly in young males than in young females.” — John Krystal, MD, Biological Psychiatry

The specialty treats a diverse patient population and the scientific discourse should reflect that breadth of experience and insight. Breaking these patterns requires intentional effort and sustained commitment.