Articles related to COLORECTAL CANCER (CRC)

A case-based application of FRESCO trial data positions fruquintinib as a third-line option in KRAS-mutant metastatic colorectal cancer, while emphasizing treatment decisions shift toward disease control and quality of life after multiple prior lines.

GLP-1 receptor agonist use was associated with a 41% lower overall risk of obesity-related cancers in a retrospective cohort of more than 229,000 non-diabetic patients with obesity, with the largest risk reductions observed in endometrial, pancreatic, colorectal, and multiple myeloma.

Nearly 18 million US women aged 45–64 were overdue for at least one recommended breast, cervical, or colorectal cancer screening, with colorectal cancer representing the largest unmet need in a 2024 BRFSS analysis of 36.2 million women.

The American Cancer Society updated its colorectal cancer screening guidelines to include two new multitarget stool tests and a blood-based option, while maintaining colonoscopy as the gold standard and the age-45 screening initiation recommendation for average-risk adults.

An Oregon gastroenterology group was hit with a $25M wrongful death verdict after a 43-year-old patient with obesity, obstructive sleep apnea, and hypertension died during a routine outpatient colonoscopy, with liability centered on the decision to perform the procedure in a lower-acuity setting despite a risk profile that plaintiffs argued warranted a hospital environment.

After 23 years, men offered once-only sigmoidoscopy had 1.7 fewer colorectal cancers and 0.8 fewer CRC deaths per 100. In women, the mortality benefit didn’t reach significance.