Articles related to Rheumatology

Statin exposure in LPS-primed mouse muscle cells activated NLRP3 inflammasome signaling and reduced protein prenylation, producing atrophy markers and grip strength loss in a preclinical model of statin myopathy.

Glucosamine use was associated with a 25% increase in mortality risk in patients with Alzheimer’s disease-related dementia in a retrospective analysis of more than 50,000 patients, with no corresponding signal observed in those with mild cognitive impairment.

A decade after surgery, patients who got their torn meniscus trimmed fared worse than those who received a sham procedure. The sham group reported less pain, more knee use, and less arthritis progression.

A 13-year-old boy presents with recurrent erythematous, tender papules on the lateral and dorsal aspects of the distal fingers, first appearing in early December and recurring after a recent skiing trip.

A single-institution case series of 13 biopsy-proven hydroxychloroquine cardiomyopathy patients documented variable outcomes after drug cessation, ranging from full functional recovery to progression requiring advanced heart failure therapies.

The American Academy of Ophthalmology updated hydroxychloroquine retinopathy screening recommendations, emphasizing dose limits, OCT and FAF as primary screening modalities, and risk stratification by renal status and concurrent tamoxifen use.