Articles related to AUTOIMMUNE DISORDERS

Researchers have identified insufficient activation of the aryl hydrocarbon receptor (AHR) pathway as a key driver in lupus pathogenesis, offering a new target for therapeutic intervention.

In a recent study, 95% of ITP patients treated with the novel anti-CD38 monoclonal antibody, CM313, achieved two consecutive platelet counts of at least 50×10^9 per liter within just eight weeks, highlighting the therapy’s efficacy and rapid action.

Hashimoto’s Thyroiditis is linked to a complex array of symptoms ranging from thyroid enlargement and systemic metabolic disruptions to severe fatigue and cognitive decline, highlighting the need for comprehensive diagnostic strategies and personalized treatment plans.

In a recent study, color Doppler ultrasound identified Giant Cell Arteritis in 44% of suspected cases, proving its effectiveness as a first-line diagnostic tool. This method offers a significant advantage in managing patient care by potentially reducing the need for subsequent invasive testing.

The case highlights the diagnostic challenges and complexities in unraveling rare neurological presentations, necessitating a comprehensive and multidisciplinary approach to patient care.

This “From the Editor” in the Cleveland Clinic Journal of Medicine offers a nuanced view of corticosteroid therapy, highlighting the balance between their significant therapeutic benefits and the risk of adverse effects in long-term use.