Articles related to AUTOIMMUNE DISORDERS

The American Thyroid Association released updated evidence-based recommendations for thyroid disease in preconception, pregnancy, and postpartum, incorporating new trial data on LT4 treatment thresholds, TPOAb management, and ATD safety that diverge meaningfully from 2017 guidance.

A middle-aged woman with a four-year bipolar disorder diagnosis continued deteriorating despite psychiatric treatment until clinical reassessment pointed toward anti-NMDA receptor encephalitis, an autoimmune condition whose psychiatric prodrome frequently delays correct diagnosis.

The findings support, whenever possible, prioritizing higher-intensity activities in clinical and public health interventions aimed at preventing non-communicable diseases.

Early treatment phases may transiently promote immune activation, whereas sustained therapy, by reducing BMI and lowering systemic inflammation, may mitigate this effect.

Despite its reputation as a malabsorptive disorder, 27% of celiac disease patients in the United States are overweight, highlighting the importance of maintaining clinical suspicion regardless of body habitus.

Salt-and-pepper skin pigmentation can be an early indicator of systemic sclerosis, characterized by vitiligo-like depigmentation with sparing of perifollicular areas.