Articles related to Hematology

Despite its theoretical benefits, IV albumin has not shown consistent superiority over crystalloid solutions in sepsis management, prompting a reevaluation of fluid resuscitation strategies in critical care settings.

In a recent study, 95% of ITP patients treated with the novel anti-CD38 monoclonal antibody, CM313, achieved two consecutive platelet counts of at least 50×10^9 per liter within just eight weeks, highlighting the therapy’s efficacy and rapid action.

Red-cell rosette formation in malaria may allow infected erythrocytes to evade splenic sequestration, posing challenges in treatment.

An AI-powered test using dried blood spots can diagnose pancreatic, gastric, and colorectal cancers in minutes with 82–100% sensitivity, offering a cost-effective alternative for low-income regions.

The study found that andexanet alfa significantly improves hemostatic efficacy in patients with intracerebral hemorrhage on factor Xa inhibitors but increases the risk of thrombotic events. These findings highlight the need for careful patient selection and monitoring when considering andexanet alfa in clinical practice.

The introduction of exa-cel as a gene-editing therapy marks a significant advance in treating hemoglobinopathies, offering new hope for patients with SCD and β-thalassemia. This treatment focuses on reactivating fetal hemoglobin to mitigate disease symptoms effectively.