Articles related to Radiology

A randomized noninferiority trial involving 648 men with MRI-visible prostate lesions found that cognitive fusion biopsy achieved clinically significant prostate cancer detection rates similar to software-based fusion biopsy. Subgroup analyses suggested body mass index may influence the relative performance of each approach.

A two-year analysis of 12,670 screened men found that the Stockholm3 risk model detected more clinically significant prostate cancers than PSA testing alone, primarily through fewer false-negative results. The findings suggest improved screening discrimination, although follow-up remains limited to two years.

A multivariable screening test detects 90% of clinically significant prostate cancers vs 74% with PSA alone, suggesting PSA thresholds may miss aggressive disease despite similar false-positive rates.

A randomized phase II trial in 240 premenopausal women evaluated whether low-dose (Z)-endoxifen could reduce mammographic breast density with improved tolerability compared with standard tamoxifen prevention regimens.

A widely shared r/medicine thread drew candid, self-identified physician commentary on which specialties absorb the most interprofessional scrutiny, with emergency medicine and primary care drawing the heaviest fire.

The American College of Physicians issued updated breast cancer screening guidance recommending biennial mammography for average-risk women aged 50 to 74, with shared decision-making for those 40 to 49 and discontinuation discussions after 74.