Articles related to CANCER SCREENING
Expansion of Cancer Risk Profile for BRCA1 and BRCA2 Pathogenic Variants
In this case-control registry study of 63,828 patients with 14 common cancer types and 37,086 controls, pathogenic variants in BRCA1 were associated with biliary tract cancer, BRCA2 was associated with esophageal cancer, and combined BRCA1/2, with gastric cancer.
Oncology, Medical April 19th 2022
Lung Screening’s Benefits, Challenges
In March 2021, the US Preventive Services Task Force expanded the eligibility for lung cancer screening by setting the benchmark at a 20 pack-year smoking history for those ages 50 to 80 years who are current smokers or former smokers who have quit within the past 15 years. The new criteria will boost the number of eligible adults by 87% overall, according to a modeling analysis. It also could reduce lung cancer deaths by 13% versus 10% previously.
Internal Medicine March 15th 2022
Estimation of Breast Cancer Overdiagnosis in a US Breast Screening Cohort
Of the nearly 83,000 mammograms taken among nearly 36,000 women screened, 1 in 7 cases was determined to be overdiagnosed. The information revealed in this Annals of Internal Medicine study clarifies the risk for breast cancer overdiagnosis in contemporary screening practice and should facilitate shared and informed decision making about mammography screening.
Internal Medicine March 8th 2022
GU Cancer: FDA Approves Product to Increase Access to PSMA PET Imaging for Prostate Cancer
Illucix is a preparation kit for gallium-68 PSMA-11 injection, an agent indicated for PET PSMA position tumors in patients with suspected prostate cancer metastasis who are eligible for initial definitive therapy and have suspected cancer recurrence based on elevated PSA levels.
Internal Medicine January 19th 2022
Family History of CCIS Linked to Increased Risk of Invasive Colorectal Cancer
Using data from Swedish family cancer datasets to calculate standardized incidence ratios (SIRs) and the cumulative risk of invasive colorectal cancer (CRC) in first- and second-degree relatives of people with colorectal carcinoma in situ (CCIS) or invasive CRC, the Journal of the National Comprehensive Cancer Network (JNCCN) suggests that family history of CCIS should be considered similarly to family history of invasive CRC in risk stratification for earlier CRC screening.
Gastroenterology December 21st 2021
Six At-Home Cancer Screening Tests
A good primer for the oncologist on several cancer screening tests that can be administered at home and help detect cancer in its earliest, most treatable stages — often before people experience symptoms. Some tests, such as a screening colonoscopy, can even treat cancer by removing abnormal cells before they become problematic.
Internal Medicine October 29th 2021