Articles related to DIAGNOSTIC STEWARDSHIP

In a prospective study of nearly 4,000 children evaluated for suspected pulmonary embolism, the PERC-Peds rule demonstrated 99.6% sensitivity and a 0.1% false-negative rate. The findings support diagnostic assessment performance in the study population without establishing broader implementation outcomes.

A Georgia woman alleges that a pathology specimen mix-up led to an erroneous cancer diagnosis and an unnecessary hysterectomy. The lawsuit highlights the potential consequences of laboratory identification failures and diagnostic verification breakdowns.

A retrospective study of 606 pediatric patients found serum specific IgE testing for allergic rhinitis was frequently negative in children younger than 3 years and became more informative with age. Findings may aid diagnostic decision-making, though prospective validation is needed.

The American Cancer Society updated its colorectal cancer screening guidelines to include two new multitarget stool tests and a blood-based option, while maintaining colonoscopy as the gold standard and the age-45 screening initiation recommendation for average-risk adults.

A quiz-format clinical vignette from Consultant360 walked through imaging selection and analgesia decisions in a 47-year-old woman presenting with acute right upper quadrant pain, using the case to reinforce diagnostic sequencing in the acute abdomen.

Invasive mucinous adenocarcinoma carries elevated NRG1 fusion burden that standard DNA-based sequencing reliably misses, while an FDA-approved targeted therapy now exists for confirmed cases.