Articles related to CLINICAL CHALLENGE

A perimenopausal woman presenting with ST-segment elevation myocardial infarction was found to have both spontaneous coronary artery dissection and stress-induced cardiomyopathy, highlighting the diagnostic complexity and potential overlap of two uncommon causes of acute coronary syndrome in women.

A 55-year-old man developed progressive weakness, areflexia, and respiratory compromise after a fall, despite spinal imaging that initially appeared to explain his presentation.

A 16-year-old girl presented with acute aphasia and right-sided weakness consistent with a large-vessel stroke syndrome. Neuroimaging confirmed left middle cerebral artery occlusion, but the underlying etiology was not immediately apparent.

A young hyperopic patient developed prolonged acute angle-closure glaucoma after an initial misdiagnosis, leading clinicians to pursue an anatomy-based surgical approach when laser iridotomy alone failed to provide sustained pressure control.

A man in his early 30s presenting with post-viral chest pain and bilateral forearm numbness posed a diagnostic challenge when automated ECG interpretation missed findings later consistent with acute pericarditis, including diffuse concave-upward ST elevation, PR depression, and a positive Spodick sign.

A middle-aged woman with a four-year bipolar disorder diagnosis continued deteriorating despite psychiatric treatment until clinical reassessment pointed toward anti-NMDA receptor encephalitis, an autoimmune condition whose psychiatric prodrome frequently delays correct diagnosis.