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Infectious Disease Special Edition (IDSE)
Reports on the Vaccine Safety Datalink flagged the need to investigate a potential increased risk those 65 years of age and older, for ischemic stroke in the first 21 days after receiving the bivalent Pfizer-BioNTech booster. FDA has parallel monitoring systems to confirm or fail to validate a safety signal. In this case, those other systems did not confirm the Vaccine Safety Datalink flag.
Allergy & Immunology January 24th 2023
JAMA Network
The risk of symptomatic intracranial hemorrhage was lower among the 832 patients receiving direct oral anticoagulant treatment in this cohort study involving 33,207 patients with ischemic stroke who received intravenous thrombolysis at 64 centers in Europe, Asia, Australia, and New Zealand when compared to controls who received no anticoagulation. This outcome held true across subgroups and various selection methodologies.
Cardiology January 18th 2023
Mayo Clinic Labs
It wasn’t carpal tunnel. It wasn’t just anxiety, and Ed wasn’t having a stroke. Even after a complete neurological assessment, it wasn’t “mild cognitive impairment.” For months, Ed’s life was plagued with psychiatric and movement disorders that puzzled his wife and his physicians. Read the narrative about how Ed was finally diagnosed, what happened next, and where he is now.
Neurology January 10th 2023
MDLinx
In addition to stroke, central causes of vertigo include brainstem glioma, medulloblastoma, vestibular schwannoma, and vestibular migraine. Peripheral causes include BPPV, Meniere disease, acute labyrinthitis, vestibular neuritis, and multiple sclerosis.
Family Medicine/General Practice November 29th 2022
Annals of Internal Medicine
When compared with rivaroxaban in a propensity score–matched cohort of 19,894 patients, apixaban was associated with an approximately 50% lower rate of ischemic stroke or systemic embolism and bleeding compared to rivaroxaban.
Cardiology October 26th 2022
The New England Journal of Medicine
Over a 5-year period, patients who presented with basilar artery stroke between 6 to 24 hours after symptom onset were randomized to thrombectomy plus medical therapy or medical therapy alone. The thrombectomy group had a greater chance of survival and of achieving good functional status (using a modified Rankin scale) at 90 days, but suffered more procedural complications and cerebral hemorrhages.
Neurology October 25th 2022