Articles related to Dermatology

An 87-year-old white man presented to a hospital emergency surgical department with two round, grayish-brown nodules on his abdomen. He had no other complaints except feeling tired and dizzy for the last few months. He had a 120 pack-year smoking history but was not taking any medications and had not experienced a cough, chest pain, shortness of breath, or other breathing problems.

Can you solve the case? A 40-year-old man presents with intermittent burning on his feet over the past three years, typically in colder months, often after outdoor activities. He has no history of disease, denies drug use, and does not smoke. What’s your diagnosis?

Similarly, can you determine how to treat a 22-year-old man with Marfan syndrome who complains of an asymptomatic rash on his arms and neck that began over a year ago? Take the quiz to test your diagnostic prowess.

Interest in immune-modulating neoadjuvant therapy for melanoma is growing. It is possible that BRAF/MEK inhibition will be more effective in the neoadjuvant than in the adjuvant setting because of the effect of the tumor biomass. And the benefits neoadjuvant therapy would offer in assessing biologic response assessment to treatment are significant. In this review the authors discuss the rationale for this treatment approach, summarize completed and ongoing neoadjuvant clinical trials, and contextualize these findings within the growing body of knowledge about targeted and immune checkpoint therapy.

Can you figure out the cause of this progressing discoloration on the bilateral anterior thighs of this 48-year-old patient? The patient denies pain, itching, or blistering, but her medical history is relevant for hypothyroidism. Any guesses?

This 16-year-old patient with an 8-year history of psoriasis, currently being treated with topical steroids and UV light therapy, presents with a swollen lip with white crusting. View the image and check your diagnosis.