Articles related to Pediatrics

Analysis of genetic testing data from nearly 180,000 individuals with autism suggests that Phelan-McDermid syndrome may affect approximately 1 in 7,300 people. The findings indicate the condition may be substantially more common than previously estimated and highlight ongoing diagnostic gaps.

The FDA expanded approval of the CRISPR-based gene therapy Casgevy to include patients as young as 2 years with sickle cell disease or transfusion-dependent beta thalassemia. The decision was supported by pediatric phase 3 data demonstrating sustained reductions in disease burden.

Genetic analyses of nearly 80,000 infants identified variants associated with toddler activity levels and other early behavioral traits. Several of these genetic signals overlapped with those previously linked to ADHD and autism, although the findings do not establish causality.

An Arizona toddler was pronounced dead following resuscitation efforts and later discovered alive in a hospital morgue hours afterward. The unusual case has prompted investigation into death determination, communication, and post-resuscitation safety processes.

A large ECHO Cohort analysis associated several pregnancy urinary chemical biomarkers with modest shifts in gestational age and fetal growth measures. The observational findings did not establish causality.

Prenatal fish oil supplementation was associated with small differences in cerebral blood flow and oxygen metabolism at age 10. Cognitive and psychopathology outcomes showed no significant association.