Articles related to ATTENTION-DEFICIT HYPERACTIVITY DISORDER (ADHD)

Researchers identified regulatory variants affecting the X-linked gene MECP2 that may contribute to autism risk in males, offering a potential genetic explanation for part of the long-observed male predominance in autism spectrum disorder. Mutations associated with approximately 30% reductions in MECP2 expression produced autism-related phenotypes without causing classic Rett syndrome.

Growing evidence suggests that exposure to natural environments may improve mood, attention, and selected cognitive functions, although the current literature remains insufficient to establish nature-based interventions as validated treatments for psychiatric disorders.

In a longitudinal analysis of more than 167,000 children in Wales, maternal depression was associated with higher rates of special educational needs and neurodevelopmental disorders. Additional risk observed among antidepressant-exposed pregnancies remained difficult to separate from underlying depression severity.

Loss of the membrane-regulating protein NSF in dopamine D2 receptor-expressing neurons was associated with hyperactivity, impulsive behavior, and reduced striatal dopamine signaling in mice. The findings offer mechanistic insight into ADHD biology, although clinical relevance remains unproven.

Childhood ADHD was associated with higher rates of adult psychiatric and neurologic hospitalization in a Finnish birth cohort followed into adulthood, while most somatic health outcomes showed little evidence of a sustained association.

The FDA issued a Class II recall for an amphetamine-based ADHD medication after a labeling mix-up resulted in immediate-release capsules being packaged as extended release. The recall affects a single lot totaling 1,392 bottles.