Articles related to ANTIDEPRESSANTS
The Anxiolytic and Antidepressant Effects of Transcranial Magnetic Stimulation in Patients with Anxious Depression
Clinically significant anxiolytic and antidepressant benefits were seen in anxious depression patients after TMS in all samples, with average reductions in GAD-7 and PHQ-9 scores of 50% or more. The PHQ-9 scores for both the anxious and nonanxious depression groups improved equally. The worried group, however, scored higher both at the beginning of the study and after TMS, leading to significantly lower categorical rates of response and remission in depressive symptoms. The shift in anxiety and depressive symptoms substantially correlated among individuals who had anxious depression.
Psychiatry January 18th 2023
Four Antidepressants Found to Have Best Efficacy, Acceptability, and Tolerability in Patients with MDD
This meta analysis of antidepressants in MDD included 34 double-blind, randomized, placebo-controlled studies covering 20 antidepressants. Outcomes were 6-month relapse rates and tolerability measures. Fourteen of the agents had better relapse rates than placebo. Four — desvenlafaxine, paroxetine, venlafaxine, and vortioxetine — displayed the best efficacy and tolerability.
Neurology November 29th 2022
Psilocybin in Treatment-Resistant Depression
“Because medicine abhors a therapeutic vacuum,” the hallucinogens psilocybin and LSD are being revisited as potential candidates for treating depression. But effect size seems less than that of currently approved antidepressants.
Neurology November 14th 2022
Antidepressant Exposure In Utero Should Prompt Early Screening for Neurodevelopmental Disorders
Pregnant women who filled prescriptions for bupropion, citalopram, escitalopram, fluoxetine, or sertraline during pregnancy (antidepressant-exposed cohort) and pregnant women who did not fill an antidepressant prescription within 90 days of the start of their pregnancy through delivery (control group) were the subjects of the study conducted by researchers from Brigham and Women’s Hospital in the United States. The main finding concerned the frequency of ADHD, autism spectrum disorder (ASD), behavioral disorder, developmental coordination disorder, developmental speech or language disorder, intellectual disability, any NDDs, and specific learning disorders among the children of the women in the study.
Neurology November 8th 2022
Women’s Health Update: A Literature Review Impacting Primary Care
This broad review of recent studies in women’s health topics aims to help the primary care physician in discussing and guiding therapy for women in topics from cardiovascular disease to pelvic pain. The review covers such questions as: How does migraine with aura affect CVD risk in women? How do you respond to patient questions about fracture risk and bisphosphonates? Are antidepressants safe for women who are considering pregnancy? Is gabapentin effective for chronic pelvic pain?
Cardiology October 20th 2022
Association of Antidepressant Use During Pregnancy with Risk of Neurodevelopmental Disorders in Children
Some studies in children have reported a relationship between antidepressant use in pregnancy and neurodevelopment disorders after birth. In this analysis of 145,702 antidepressant-exposed and 3,032,745 unexposed pregnancies, crude results suggested up to a doubling in risk of neurodevelopmental outcomes. Significantly, however, no association was observed after balancing for confounding variables.
Neurology October 20th 2022