Articles related to ANTIDEPRESSANTS

This target trial emulation study provides critical insights into weight change associated with eight first-line antidepressants, emphasizing the minimal weight gain with bupropion. Clinicians should integrate these findings into treatment decisions to address patient concerns about weight gain.

Clinicians should be vigilant about melatonin interactions with various medications such as antidepressants, blood thinners, and blood pressure drugs to ensure patient safety and effective treatment.

In this NEJM Double Take episode, experts discuss the critical role of neuroplasticity in depression and examine advanced treatment options for patients who do not respond to traditional therapies. Topics include the efficacy of ECT and TMS, as well as emerging evidence for ketamine, esketamine, and psilocybin.

Recent studies indicate that while ketamine and ECT are equally effective for treating MDD, ketamine did not prove non-inferior to ECT for MDEs. Both treatments have distinct side effect profiles that are critical for clinical decision-making.

Physicians must be vigilant of the impact that various medications can have on sexual function, including those less commonly associated with sexual side effects, to ensure holistic patient care and adherence to treatment.

In this video, Dr. Charles Raison reveals how hyperthermia may harness the body’s immune response to combat major depressive disorder, suggesting a potential shift in non-pharmacological treatment strategies.