Articles related to Internal Medicine

Atorvastatin reduced major cardiovascular events among adults aged 70 years and older without known cardiovascular disease, diabetes, or dementia, but the benefit did not translate into a statistically significant improvement in disability-free survival over nearly six years of follow-up.

An expert commentary argues that persistent physical symptoms should be approached through a balanced framework that validates patient suffering, excludes dangerous medical illness, and incorporates evidence-informed understanding of brain-body mechanisms without dismissing symptoms as psychological.

The American Gastroenterological Association issued nine best practice statements on colorectal and esophageal surveillance in older adults. Recommendations emphasize individualized decisions, life expectancy, treatment candidacy, procedural risks, and patient preferences.

The FDA approved tirzepatide to reduce major cardiovascular event risk in high-risk adults with type 2 diabetes. SURPASS-CVOT established noninferiority to dulaglutide rather than cardiovascular superiority.

Double-filtration plasmapheresis reduced circulating concentrations of several PFAS in small patient samples, while microplastic changes varied by polymer. The exploratory findings do not support apheresis for environmental pollutant removal.

Hospital ownership of health insurance plans increased from 18.3% in 2018 to 27.2% in 2023, with higher adoption among academic institutions. Effects on care, physician incentives, and costs remain uncertain.