Articles related to CHRONIC OBSTRUCTIVE PULMONARY DISORDER (COPD)
Gabapentinoids and Risk for Severe Exacerbation in Chronic Obstructive Pulmonary Disease
In a comprehensive analysis of COPD patients, the use of gabapentinoids was found to be associated with a 1.39 times higher risk of severe exacerbations requiring hospitalization. This finding underscores the need for cautious prescribing of these medications in the COPD population, considering their potential respiratory risks.
Internal Medicine January 24th 2024
Comparative Effectiveness and Safety of Generic Versus Brand-Name Fluticasone–Salmeterol to Treat Chronic Obstructive Pulmonary Disease
The study reveals that generic Wixela Inhub is comparable to Advair Diskus in both effectiveness and safety for treating COPD. Consider this cost-effective alternative in your treatment plans.
Clinical Pharmacology August 31st 2023
Dupilumab for COPD with Type 2 Inflammation Indicated by Eosinophil Counts
Uncover the potential of dupilumab in managing COPD patients with type 2 inflammation as this Phase 3 trial reveals fewer exacerbations, improved lung function, and enhanced life quality among the treated cohort.
Allergy & Immunology July 27th 2023
Oxygen Manifesto, Part 1: Advice from 3 Respiratory Specialists
Uncover vital insights about supplemental oxygen use, demystify misconceptions, and learn best practices for managing respiratory diseases. Good day, physicians. Let’s talk about the controversial issue of supplemental oxygen use, frequently discussed by patients, clinicians, advocacy groups, and even politicians. In this summary, we’ll untangle misconceptions and illuminate best practices. To start with, the body’s oxygen utilization depends on three things: lung function, heart efficiency, and muscle oxygen use. These factors can improve with exercise, but worsen with inactivity. Remember, exercise matters. Why does oxygen matter? For patients with chronic obstructive pulmonary disease (COPD), pulmonary fibrosis (PF), or pulmonary hypertension (PH), impaired oxygenation can lead to hypoxemia and hypoxia. Hence, supplemental oxygen becomes a necessity. How do we assess oxygen levels? Two tests can be employed: arterial blood gas (ABG) or pulse oximetry. Normal partial pressure of oxygen, as per ABG, is around 75-100 mmHg, and a drop below 60 necessitates supplemental oxygen. Oxygen saturation, measurable via either test, should ideally be 95% or above, and values dropping to 90 or below indicate the need for supplemental oxygen. Now, let’s dispel some myths. Shortness of breath doesn’t always equate to hypoxia. A patient can experience breathlessness even with normal oxygen […]
Family Medicine/General Practice May 24th 2023
Outcomes of a Pharmacy-Driven Inpatient Chronic Obstructive Pulmonary Disease (COPD) Transitions of Care (TOC) Management Process
A pharmacy-driven COPD TOC service did not significantly reduce the 30-day re-presentation rate, according to this study. It did discover that a sizable proportion of patients with COPD exacerbation who were admitted might require an inhaler change, and it illustrates the value of this kind of TOC service for seeing and fixing medication-related issues particular to this disease state. The percentage of patients receiving the entire intended intervention had room for improvement.
Clinical Pharmacology April 27th 2023